![]() The following information is excerpted from the DOE Office of Science (DE-FOA-0002414), however investigators are advised to refer to the funding notice for any additional requirements.Ī biographical sketch (biosketch) is to provide information that can be used by reviewers to evaluate the PI’s potential for leadership within the scientific community. Onsite searching on the VPR public websites.VPR Research Administration Organization Chart. ![]() RA and TA Salary Levels and Health Insurance Rates.Graduate Research Assistant Tuition Subsidy Rates.Facilities and Administrative (F&A) Rates.While both of these observations remain difficult to interpret, they have added some urgency to expand the cohort and continue to follow-up. In addition, there were three cases of ovarian cancer in the granddaughters, even though substantially less than one had been expected. However, investigators noted an elevated risk for infertility-though not statistically significant, this outcome was also seen in DES-daughters. Given their average age, there have been few relevant disease outcomes. To examine the effects in the third generation (the daughters of the prenatally exposed daughters), investigators assembled a small cohort in 2000. In the sons, investigators observed an excess risk for urogenital anomalies and infertility, and a likely excess of testicular cancer. ![]() Concern over other hormone-related cancers remains though to date analyses have been limited due to small numbers of cases. To date the study has identified excess female breast cancer after age 40 that shows a dose-response effect, as well as increased risk for high-grade lesions of the cervix and vagina. The study also provides a model for assessing a number of hypotheses that address concerns about prenatal hormonal influences on disease risk, both an intriguing area of science and an increasingly controversial environmental issue that affects a substantial proportion of the population. As DES-exposed offspring are currently reaching the age when cancer rates begin to rise, it is important to continue to monitor long-term risk of cancer and other adverse health outcomes in this unique population. Troisi, other NCI investigators, and collaborators from five field study centers have been actively following DES-exposed and unexposed mothers, daughters and sons, and granddaughters for adverse health effects resulting from this exposure.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |